Trends in mortality in children hospitalized with meningococcal infections, 1957 to 1987.

摘要: We reviewed charts of 261 children seen at Children's Hospital Wisconsin from 1957 to 1987 with culture-proven meningococcemia or meningococcal meningitis, and we analyzed trends in mortality disease severity for that interval. Overall case fatality was 10%, ranging 9% the period 1963, 16% 1980 (P = 0.15). The percent patients admitted severe increased 14% 38% 0.001). When stratified by severity, case-fatality rates did not change time. conclude technologic advances past 30 years had no measurable impact on infection our hospital crude can be misleading if is considered.