Effects of EPHX1, SCN1A and CYP3A4 genetic polymorphisms on plasma carbamazepine concentrations and pharmacoresistance in Chinese patients with epilepsy.

作者: Wenting Yun , Feng Zhang , Cheng Hu , Xiaopei Luo , Peng Xue

DOI: 10.1016/J.EPLEPSYRES.2013.09.011

关键词:

摘要: … Interestingly, we found no significant associations between the CYP3A4*1G variant allele and CBZ maintenance doses, adjusted plasma concentrations or pharmacoresistance in the …

参考文章(27)
Ida Manna, Antonio Gambardella, Amedeo Bianchi, Pasquale Striano, Rossana Tozzi, Umberto Aguglia, Francesca Beccaria, Paolo Benna, Roberto Campostrini, Maria P. Canevini, Francesca Condino, Christine Durisotti, Maurizio Elia, Anna T. Giallonardo, Alfonso Iudice, Angelo Labate, Angela La Neve, Roberto Michelucci, Gian C. Muscas, Roberta Paravidino, Gaetano Zaccara, Claudio Zucca, Federico Zara, Emilio Perucca, A functional polymorphism in the SCN1A gene does not influence antiepileptic drug responsiveness in Italian patients with focal epilepsy Epilepsia. ,vol. 52, pp. 40- 44 ,(2011) , 10.1111/J.1528-1167.2011.03097.X
Bradley M. Kerr, Kenneth E. Thummel, Colleen J. Wurden, Susan M. Klein, Deanna L. Kroetz, Frank J. Gonzalez, RenéH. Levy, HUMAN LIVER CARBAMAZEPINE METABOLISM. ROLE OF CYP3A4 AND CYP2C8 IN 10, 11-EPOXIDE FORMATION Biochemical Pharmacology. ,vol. 47, pp. 1969- 1979 ,(1994) , 10.1016/0006-2952(94)90071-X
N R Kitteringham, B K Park, M Pirmohamed, C Davis, N Howard, Interindividual and interspecies variation in hepatic microsomal epoxide hydrolase activity: studies with cis-stilbene oxide, carbamazepine 10, 11-epoxide and naphthalene. Journal of Pharmacology and Experimental Therapeutics. ,vol. 278, pp. 1018- 1027 ,(1996)
Z-L. Dong, H. Li, Q-X. Chen, Y. Hu, S-J. Wu, L-Y. Tang, W-Y. Gong, G-H. Xie, X-M. Fang, Effect of CYP3A4*1G on the fentanyl consumption for intravenous patient‐controlled analgesia after total abdominal hysterectomy in Chinese Han population Journal of Clinical Pharmacy and Therapeutics. ,vol. 37, pp. 153- 156 ,(2012) , 10.1111/J.1365-2710.2011.01268.X
Bao-xia He, Lei Shi, Jian Qiu, Liang Tao, Rui Li, Liang Yang, Shu-jin Zhao, A functional polymorphism in the CYP3A4 gene is associated with increased risk of coronary heart disease in the Chinese Han population. Basic & Clinical Pharmacology & Toxicology. ,vol. 108, pp. 208- 213 ,(2011) , 10.1111/J.1742-7843.2010.00657.X
Bo-Ting Zhou, Qiu-Hong Zhou, Ji-Ye Yin, Guo-Liang Li, Xiao-Jing Xu, Jian Qu, Ding Liu, Hong-Hao Zhou, Zhao-Qian Liu, Comprehensive analysis of the association of SCN1A gene polymorphisms with the retention rate of carbamazepine following monotherapy for new-onset focal seizures in the Chinese Han population. Clinical and Experimental Pharmacology and Physiology. ,vol. 39, pp. 379- 384 ,(2012) , 10.1111/J.1440-1681.2012.05680.X
Yuan Gao, Li-rong Zhang, Qiang Fu, CYP3A4*1G polymorphism is associated with lipid-lowering efficacy of atorvastatin but not of simvastatin. European Journal of Clinical Pharmacology. ,vol. 64, pp. 877- 882 ,(2008) , 10.1007/S00228-008-0502-X
Masatomo Miura, Shigeru Satoh, Hideaki Kagaya, Mitsuru Saito, Kazuyuki Numakura, Norihiko Tsuchiya, Tomonori Habuchi, Impact of the CYP3A4*1G polymorphism and its combination with CYP3A5 genotypes on tacrolimus pharmacokinetics in renal transplant patients. Pharmacogenomics. ,vol. 12, pp. 977- 984 ,(2011) , 10.2217/PGS.11.33
Yukiko Nakajima, Yoshiro Saito, Kisho Shiseki, Hiromi Fukushima-Uesaka, Ryuichi Hasegawa, Shogo Ozawa, Kenji Sugai, Masaaki Katoh, Osamu Saitoh, Teiichi Ohnuma, Mitsuru Kawai, Taisuke Ohtsuki, Chieko Suzuki, Narihiro Minami, Hideo Kimura, Yu-ichi Goto, Naoyuki Kamatani, Nahoko Kaniwa, Jun-ichi Sawada, Haplotype structures of EPHX1 and their effects on the metabolism of carbamazepine-10,11-epoxide in Japanese epileptic patients European Journal of Clinical Pharmacology. ,vol. 61, pp. 25- 34 ,(2005) , 10.1007/S00228-004-0878-1