Guanine nucleotide–binding protein G(i)α2 aggravates hepatic ischemia-reperfusion injury in mice by regulating MLK3 signaling
作者： Qikai Sun , Qifeng He , Jianbo Xu , Qiaoyu Liu , Yijun Lu
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摘要: … and healthy donors were collected at Nanjing Drum Tower Hospital. Tissues from healthy donors … Declaration were approved by the Ethics Committee of Nanjing Drum Tower Hospital. …
fasebj.org 参考文章(38)
LUIS H. TOLEDO-PEREYRA, FRANCISCO J. RODRIGUEZ, DOLORES CEJALVO, Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine. Transplantation. ,vol. 55, pp. 1265- 1271 ,(1993) , 10.1097/00007890-199306000-00011
Naoki Mochizuki, Yusuke Ohba, Etsuko Kiyokawa, Takeshi Kurata, Takeshi Murakami, Takefumi Ozaki, Akira Kitabatake, Kazuo Nagashima, Michiyuki Matsuda, Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i) Nature. ,vol. 400, pp. 891- 894 ,(1999) , 10.1038/23738
Il-Young Hwang, Chung Park, John H. Kehrl, Impaired trafficking of Gnai2+/- and Gnai2-/- T lymphocytes: implications for T cell movement within lymph nodes. Journal of Immunology. ,vol. 179, pp. 439- 448 ,(2007) , 10.4049/JIMMUNOL.179.1.439
Y. Zhai, R. W. Busuttil, J. W. Kupiec-Weglinski, Liver Ischemia and Reperfusion Injury: New Insights into Mechanisms of Innate—Adaptive Immune‐Mediated Tissue Inflammation American Journal of Transplantation. ,vol. 11, pp. 1563- 1569 ,(2011) , 10.1111/J.1600-6143.2011.03579.X
Vasudharani Devanathan, Ina Hagedorn, David Köhler, Katja Pexa, Deya Cherpokova, Peter Kraft, Madhurendra Singh, Peter Rosenberger, Guido Stoll, Lutz Birnbaumer, Roland P. Piekorz, Sandra Beer-Hammer, Bernhard Nieswandt, Bernd Nürnberg, Platelet Gi protein Gαi2 is an essential mediator of thrombo-inflammatory organ damage in mice Proceedings of the National Academy of Sciences of the United States of America. ,vol. 112, pp. 6491- 6496 ,(2015) , 10.1073/PNAS.1505887112
N. W. Plummer, K. Spicher, J. Malphurs, H. Akiyama, J. Abramowitz, B. Nurnberg, L. Birnbaumer, Development of the mammalian axial skeleton requires signaling through the Gα(i) subfamily of heterotrimeric G proteins. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 109, pp. 21366- 21371 ,(2012) , 10.1073/PNAS.1219810110
M. Simon, M. Strathmann, N. Gautam, Diversity of G proteins in signal transduction. Science. ,vol. 252, pp. 802- 808 ,(1991) , 10.1126/SCIENCE.1902986
Ifeanyi J. Arinze, Yumiko Kawai, Transcriptional Activation of the Human Gαi2 Gene Promoter through Nuclear Factor-κB and Antioxidant Response Elements Journal of Biological Chemistry. ,vol. 280, pp. 9786- 9795 ,(2005) , 10.1074/JBC.M414006200
Louis M. Luttrell, Reviews in Molecular Biology and Biotechnology: Transmembrane Signaling by G Protein-Coupled Receptors Molecular Biotechnology. ,vol. 39, pp. 239- 264 ,(2008) , 10.1007/S12033-008-9031-1
Eva J Neer, Heterotrimeric C proteins: Organizers of transmembrane signals Cell. ,vol. 80, pp. 249- 257 ,(1995) , 10.1016/0092-8674(95)90407-7