Quantification of number density of random microstructure from a photoacoustic signal by using Nakagami statistics.
作者： Xiaoxiang Gao , Na Dai , Chao Tao , Xiaojun Liu
DOI: 10.1364/OL.44.002951
关键词:
摘要: Tissue microstructure characterization is a valuable tool in diagnosis and staging of many diseases. In this study, we propose photoacoustic Nakagami statistics method to noninvasively evaluate the number density random microstructure. The parameters are acquired by fitting signal envelope histogram with distribution function. Theoretical calculations phantom experiments demonstrate that shape parameter only related monotonically increases density. Based on finding, tomography modality imaging contrast parameter. Experiments show proposed can provide more comprehensive accurate description tissue
osapublishing.org
harvard.edu参考文章(33)
Po-Hsiang Tsui, Chih-Kuang Yeh, Yin-Yin Liao, Chien-Cheng Chang, Wen-Hung Kuo, King-Jen Chang, Chiung-Nien Chen, Ultrasonic Nakagami Imaging: A Strategy to Visualize the Scatterer Properties of Benign and Malignant Breast Tumors Ultrasound in Medicine and Biology. ,vol. 36, pp. 209- 217 ,(2010) , 10.1016/J.ULTRASMEDBIO.2009.10.006
Shaohua Wang, Chao Tao, Xueding Wang, Xiaojun Liu, Quantitative detection of stochastic microstructure in turbid media by photoacoustic spectral matching Applied Physics Letters. ,vol. 102, pp. 114102- ,(2013) , 10.1063/1.4798272
Christophe Corpechot, Fabrice Carrat, Armelle Poujol-Robert, Farid Gaouar, Dominique Wendum, Olivier Chazouillères, Raoul Poupon, Noninvasive elastography‐based assessment of liver fibrosis progression and prognosis in primary biliary cirrhosis Hepatology. ,vol. 56, pp. 198- 208 ,(2012) , 10.1002/HEP.25599
Ratan K. Saha, Subhajit Karmakar, Madhusudan Roy, Computational Investigation on the Photoacoustics of Malaria Infected Red Blood Cells PLoS ONE. ,vol. 7, pp. e51774- ,(2012) , 10.1371/JOURNAL.PONE.0051774
Ratan K. Saha, Computational modeling of photoacoustic signals from mixtures of melanoma and red blood cells The Journal of the Acoustical Society of America. ,vol. 136, pp. 2039- 2049 ,(2014) , 10.1121/1.4894794
M.I. Khan, G.J. Diebold, The photoacoustic effect generated by an isotropic solid sphere Ultrasonics. ,vol. 33, pp. 265- 269 ,(1995) , 10.1016/0041-624X(95)00034-Z
Bo Ning, Matthew J Kennedy, Adam J Dixon, Naidi Sun, Rui Cao, Brian T Soetikno, Ruimin Chen, Qifa Zhou, K Kirk Shung, John A Hossack, Song Hu, None, Simultaneous photoacoustic microscopy of microvascular anatomy, oxygen saturation, and blood flow Optics Letters. ,vol. 40, pp. 910- 913 ,(2015) , 10.1364/OL.40.000910
R.C. Molthen, P.M. Shankar, J.M. Reid, Characterization of Ultrasonic B-Scans Using Non-Rayleigh Statistics Ultrasound in Medicine and Biology. ,vol. 21, pp. 161- 170 ,(1995) , 10.1016/S0301-5629(94)00105-7
Ratan K. Saha, Michael C. Kolios, A simulation study on photoacoustic signals from red blood cells Journal of the Acoustical Society of America. ,vol. 129, pp. 2935- 2943 ,(2011) , 10.1121/1.3570946
Xiaoxiang Gao, Chao Tao, Xueding Wang, Xiaojun Liu, Quantitative imaging of microvasculature in deep tissue with a spectrum-based photo-acoustic microscopy Optics Letters. ,vol. 40, pp. 970- 973 ,(2015) , 10.1364/OL.40.000970