Basal cell carcinoma with mixed histology : A possible pathogenesis for recurrent skin cancer

作者: PHILIP R. COHEN , KEITH E. SCHULZE , BRUCE R. NELSON

DOI: 10.1111/J.1524-4725.2006.32110.X

关键词:

摘要: BACKGROUND Basal cell carcinoma with mixed histology (BCC-MH) demonstrates more than one pathologic pattern of tumor. Appropriate therapy for the nonaggressive tumor subtype diagnosed from a superficial biopsy may not be adequate to treat unsuspected aggressive subtype, resulting in recurrent skin cancer. OBJECTIVE We prospectively evaluated incidence and characteristics BCC-MH. METHODS Mohs surgical sections were RESULTS BCC-MH was observed 43% (49/144) cancers. Only 10% (5/49) reports these cancers Most previously untreated (90% [44/49] tumors) located on nose. CONCLUSION More 40% basal carcinomas referred removal residual An growth detected after biopsy. Subsequently, cancer recur if initial treatment is inadequate undiscovered carcinoma. micrographic surgery recommended treatment.

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