Circulating microRNAs as potential non-invasive biomarkers for the early detection of hypertension-related stroke.

摘要: Hypertension is one of the most important risk and modifiable factors for stroke. Crucial in managing cerebrovascular damage caused by long-lasting inadequately treated hypertension not only lowering arterial blood pressure but also early predicting subtypes hypertension-related stroke applying more effective interventions. Accumulating evidence suggested that circulating microRNAs (miRNAs) could be developed as biomarkers recognition onset a variety diseases. The role miRNAs has been extensively reviewed, involving cardiac hypertrophy, hypertensive heart failure, kidney failure renal fibrosis. miRNA research still its infancy, although there are few literatures reviewing processes This review summarizes current advances regulation critical pathogenic process underlying hypertension, ischemic hemorrhagic stroke, highlights potential using noninvasive detection