Psychological reactions in men screened for prostate cancer

摘要: Objective To investigate the possible negative psychological impact of screening for prostate Cancer with special focus on false positive and true test results. Subjects methods As part an early detection study psycho-physiological reactions to various phases diagnostic procedures were examined in 2400 randomly selected men divided into groups. Their assessed by measurements serum cortisol their questionnaires directed at determining emotional states sleep disturbance. In a stratified sample population (100 men) made time examination again 2 weeks later. patients undergoing biopsy (307 after screening, but before they informed results, 4 16 screening. Results Serum levels higher than corresponding comparable Swedish during normal daily activity, indicating that invitation per se might create stress. Two elevated had decreased normal. The highest found who undergone biopsy, immediately results screening. After informed, fell, regardless biopsy. patterns state disturbance similar except was delayed. Conclusion programmes it is important define clearly high-risk groups minimize risk adverse those subjects low having disease. also emphasize need reduce number choosing tests high specificity. interval between informing subject should be minimized decrease duration increased stress