Pathogenomics of helicobacter.

作者: Christine Josenhans , Dagmar Beier , Bodo Linz , Thomas F. Meyer , Sebastian Suerbaum

DOI: 10.1016/J.IJMM.2007.02.006

关键词:

摘要: The pathogenic bacterium Helicobacter pylori infects half of the human population and is one genetically most diverse bacterial species known. H. was first whose genome sequenced in 1997, for which two complete sequences from independent isolates were available within-species comparisons. For almost 10 years, genomic post-genomic analysis has contributed enormously to our understanding pathogenesis infection. This review summarizes information, emphasizing work performed framework PathoGenoMik funding initiative (2001-2006) German Ministry Education Research.

参考文章(95)
Crabtree Je, Role of cytokines in pathogenesis of Helicobacter pylori-induced mucosal damage. Digestive Diseases and Sciences. ,vol. 43, ,(1998)
Wataru Shibata, Yoshihiro Hirata, Haruhiko Yoshida, Motoyuki Otsuka, Yujin Hoshida, Keiji Ogura, Shin Maeda, Tomoya Ohmae, Ayako Yanai, Yuzo Mitsuno, Naohiko Seki, Takao Kawabe, Masao Omata, NF-kB and ERK-signaling pathways contribute to the gene expression induced bycagPAI-positive-Helicobacter pyloriinfection World Journal of Gastroenterology. ,vol. 11, pp. 6134- 6143 ,(2005) , 10.3748/WJG.V11.I39.6134
Zobair M. Younossi, J. Carlos Teran, Theodore G. Ganiats, William D. Carey, Ultrasound-Guided Liver Biopsy for Parenchymal Liver Disease (An Economic Analysis) Digestive Diseases and Sciences. ,vol. 43, pp. 46- 50 ,(1998) , 10.1023/A:1018815802500
Catherine C. McGowan, Antoaneta S. Necheva, Mark H. Forsyth, Timothy L. Cover, Martin J. Blaser, Promoter analysis of Helicobacter pylori genes with enhanced expression at low pH Molecular Microbiology. ,vol. 48, pp. 1225- 1239 ,(2003) , 10.1046/J.1365-2958.2003.03500.X
Kai Simons, Derek Toomre, Lipid rafts and signal transduction Nature Reviews Molecular Cell Biology. ,vol. 1, pp. 31- 39 ,(2000) , 10.1038/35036052
Stéphanie Bury-Moné, Jean-Michel Thiberge, Monica Contreras, Aboubakar Maitournam, Agnès Labigne, Hilde De Reuse, Responsiveness to acidity via metal ion regulators mediates virulence in the gastric pathogen Helicobacter pylori. Molecular Microbiology. ,vol. 53, pp. 623- 638 ,(2004) , 10.1111/J.1365-2958.2004.04137.X
Eike Niehus, Helga Gressmann, Fang Ye, Ralph Schlapbach, Michaela Dehio, Christoph Dehio, Allison Stack, Thomas F. Meyer, Sebastian Suerbaum, Christine Josenhans, Genome-wide analysis of transcriptional hierarchy and feedback regulation in the flagellar system of Helicobacter pylori. Molecular Microbiology. ,vol. 52, pp. 947- 961 ,(2004) , 10.1111/J.1365-2958.2004.04006.X
Michael Pflock, Patricia Dietz, Jennifer Schär, Dagmar Beier, Genetic evidence for histidine kinase HP165 being an acid sensor ofHelicobacter pylori FEMS Microbiology Letters. ,vol. 234, pp. 51- 61 ,(2004) , 10.1111/J.1574-6968.2004.TB09512.X
S. Censini, C. Lange, Z. Xiang, J. E. Crabtree, P. Ghiara, M. Borodovsky, R. Rappuoli, A. Covacci, cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 93, pp. 14648- 14653 ,(1996) , 10.1073/PNAS.93.25.14648
Barbara Waidner, Klaus Melchers, Igor Ivanov, Hannes Loferer, Klaus W. Bensch, Manfred Kist, Stefan Bereswill, Identification by RNA Profiling and Mutational Analysis of the Novel Copper Resistance Determinants CrdA (HP1326), CrdB (HP1327), and CzcB (HP1328) in Helicobacter pylori Journal of Bacteriology. ,vol. 184, pp. 6700- 6708 ,(2002) , 10.1128/JB.184.23.6700-6708.2002