Solvent interaction analysis as a proteomic approach to structure-based biomarker discovery and clinical diagnostics
作者： Boris Y. Zaslavsky , Vladimir N. Uversky , Arnon Chait
DOI: 10.1586/14789450.2016.1116945
关键词:
摘要: Proteins have several measurable features in biological fluids that may change under pathological conditions. The current disease biomarker discovery is mostly based on protein concentration the sample as feature. Changes structures, such post-translational modifications and protein-partner interactions are known to accompany processes. glycosylation profiles well-established for many plasma proteins various types of cancer other diseases. solvent interaction analysis method partitioning aqueous two-phase systems highly sensitive changes structure protein-protein- while independent sample. It provides quantitative index: partition coefficient representing with partners. fundamentals presented multiple examples applications discover monitor structural biomarkers disease-specific diagnostic indicators.
sci-hub.se 参考文章(62)
Gina Gough, Laura Heathers, Deonna Puckett, Chi Westerhold, Xiaowei Ren, Zhangsheng Yu, David W. Crabb, Suthat Liangpunsakul, The Utility of Commonly Used Laboratory Tests to Screen for Excessive Alcohol Use in Clinical Practice Alcoholism: Clinical and Experimental Research. ,vol. 39, pp. 1493- 1500 ,(2015) , 10.1111/ACER.12780
Pedro P. Madeira, Celso A. Reis, Alírio E. Rodrigues, Larissa M. Mikheeva, Arnon Chait, Boris Y. Zaslavsky, Solvent properties governing protein partitioning in polymer/polymer aqueous two-phase systems. Journal of Chromatography A. ,vol. 1218, pp. 1379- 1384 ,(2011) , 10.1016/J.CHROMA.2011.01.020
L. Renee Ruhaak, Donald A. Barkauskas, Javier Torres, Cara L. Cooke, Lauren D. Wu, Carol Stroble, Sureyya Ozcan, Cynthia C. Williams, Margarita Camorlinga, David M. Rocke, Carlito B. Lebrilla, Jay V. Solnick, The Serum Immunoglobulin G Glycosylation Signature of Gastric Cancer Eupa Open Proteomics. ,vol. 6, pp. 1- 9 ,(2015) , 10.1016/J.EUPROT.2014.11.002
Pedro P. Madeira, Celso A. Reis, Alírio E. Rodrigues, Larissa M. Mikheeva, Boris Y. Zaslavsky, Solvent properties governing solute partitioning in polymer/polymer aqueous two-phase systems: nonionic compounds. Journal of Physical Chemistry B. ,vol. 114, pp. 457- 462 ,(2010) , 10.1021/JP907346S
Pedro P. Madeira, Ana Bessa, Dragana P.C. de Barros, Miguel A. Teixeira, Luís Álvares-Ribeiro, M. Raquel Aires-Barros, Alírio E. Rodrigues, Arnon Chait, Boris Y. Zaslavsky, Solvatochromic relationship: prediction of distribution of ionic solutes in aqueous two-phase systems. Journal of Chromatography A. ,vol. 1271, pp. 10- 16 ,(2013) , 10.1016/J.CHROMA.2012.11.028
Johannes L Stanta, Radka Saldova, Weston B Struwe, Jennifer C Byrne, F Markus Leweke, Matthius Rothermund, Hassan Rahmoune, Yishai Levin, Paul C Guest, Sabine Bahn, Pauline M Rudd, None, Identification of N-glycosylation changes in the CSF and serum in patients with schizophrenia. Journal of Proteome Research. ,vol. 9, pp. 4476- 4489 ,(2010) , 10.1021/PR1002356
Archana Shubhakar, Karli R Reiding, Richard A Gardner, Daniel IR Spencer, Daryl L Fernandes, Manfred Wuhrer, None, High-Throughput Analysis and Automation for Glycomics Studies Chromatographia. ,vol. 78, pp. 321- 333 ,(2015) , 10.1007/S10337-014-2803-9
Stefan A. Oelmeier, Florian Dismer, Jürgen Hubbuch, Application of an aqueous two‐phase systems high‐throughput screening method to evaluate mAb HCP separation Biotechnology and Bioengineering. ,vol. 108, pp. 69- 81 ,(2011) , 10.1002/BIT.22900
Radka Saldova, Akram Asadi Shehni, Vilde D Haakensen, Israel Steinfeld, Mark Hilliard, Ilona Kifer, Åslaug Helland, Zohar Yakhini, Anne-Lise Børresen-Dale, Pauline M Rudd, None, Association of N-Glycosylation with Breast Carcinoma and Systemic Features Using High-Resolution Quantitative UPLC Journal of Proteome Research. ,vol. 13, pp. 2314- 2327 ,(2014) , 10.1021/PR401092Y
Kyle Strimbu, Jorge A Tavel, What are biomarkers Current Opinion in Hiv and Aids. ,vol. 5, pp. 463- 466 ,(2010) , 10.1097/COH.0B013E32833ED177