Die renale Osteodystrophie

摘要: Based on a literature survey the present thesis analyses symptoms of renal osteodystrophy, consequence chronic failure. Within disease complex failure osteodystrophy represents one main reasons for morbidity affected patients (Ferreira, 2006). One target this dissertation is to describe origin different types its pathogenesis, clinical phenomenons and diagnostic routines. Evaluating current state therapy another focus. At point, mode action, dosage, side effects risks therapeutics have been proved by research results. There are two kinds osteodystrophy: high turnover bone low disease. Current studies indicate that incidences changed over last three decades: In 1970s 1980s caused secondary hyperparathyroidism lack vitamin D were predominant. Due intensified application D-metabolites in order treat disease, increasing occurrence diabetes mellitus higher age patients, strong parathyroid suppression has appeared more often meantime. With regard routines, biopsy histomorphometric evaluation still only secure way diagnose osteodystrophy. Up now, search new chemical parameters substitute examination remained without any result. However, there certain laboratory successfully applied controlling approaches osteodystrophy. These therapies form focus dissertation. Administration balance principal components treating Hypercalcaemia remains most serious effect these compounds which can lead possibly metastatic calcifications also disease. Vitamin must be prescribed very carefully well dosed, particularly if was with D-metabolites. In presents innovative approaches, such as solanum glaucophyllum natural source active D. reduce phosphate level, problem phosphatebinders applied. In summery, considerable deficits even exist today. Bone defects remedied slowly time complications. Therefore, early diagnosis treatment vital importance.