Osseointegration of sintered porous-surfaced and plasma spray-coated implants: An animal model study of early postimplantation healing response and mechanical stability.

摘要: The osseointegration and long-term success of bone-interfacing implants are dependent on mechanical stability the implant relative to host bone during early healing period. geometric design an surface may play important role in affecting stabilization, possibly by influencing tissue dynamics. In this study, we compared response resulting for two designs characterizing histological properties around Ti6Al4V sintered porous-surfaced Ti plasma-sprayed implants. were inserted transversely rabbit femoral condyles evaluated at 0, 4, 8, 16 days postimplantation. At 4 8 after implantation, (fibrin collagenous matrix) was more extensively integrated with three-dimensional interconnected structure porous than irregular geometry coating. addition, examination indicated that initial matrix mineralization leading occurred rapidly extensive integration rapid reflected test data, which demonstrated greater attachment strength interfacial stiffness postimplantation (p <.05). Sixteen both osseointegrated had comparable characteristics. These data demonstrate appropriate selection can improve induce accelerated response, thereby improving potential osseointegration.