Short-term and mid-term outcome of isolated symptomatic muscular calf vein thrombosis

摘要: Background Although muscular calf vein thrombosis (MCVT) is commonly seen in everyday practice, no treatment guidelines are available. This study evaluated short-term and mid-term outcome of isolated symptomatic MCVT. Method We included prospectively consecutively all patients referred to an outpatient clinic with Clinical signs were pain or edema, both, the calf. Diagnosis was established duplex ultrasound (DUS) examination. Not completely occlusive asymptomatic MCVTs excluded. Patients followed up clinically DUS at 1, 3, 9 months, 36 months. Anticoagulant therapy curative dosage associated compression prescribed for 1 month extended 2 additional months case incomplete recanalization if risk factors venous thromboembolism (VTE) present. Results Included 128 (78 women, 50 men) presenting 131 MCVTs. Their mean age 57.02 ± 15.36 years (range, 20 87 years). Thrombus present soleal veins (SoV) 73 (55.7%) medial gastrocnemius (MGV) 58 (44.3%). Initial symptoms 90 patients, edema six, plus 32. 53 (41.4%) month, 59 (46.1%) 3 13 (10.2%) ≥6 At baseline, nine pulmonary embolisms (7%), complicated MCVT, observed six MGV (10.3%) three SoV (4.1%; P = .18). Two nonfatal hemorrhagic events occurred. Three died during follow-up after anticoagulant had been discontinued. Recanalization MCVT considered complete 54.8%, 84.7%, 96% cases, respectively, significant difference between groups. Twenty-nine VTE recurrences (PE, n=6; DVT including n=23) 24 (18.8%), similar figures both groups: none 11 18 No extension a recurrence treated therapy. Twelve cases superficial thrombophlebitis occurred period. Conclusion confirms place disorders. Pulmonary embolism initial diagnosis not rare, (mean, 26.7 months) revealed that 18.8% least one recurrence. The acute needs be standardized because currently exist.