Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta
作者： Domingos Henrique , Julian Lewis , David Ish-Horowicz , Chris Kintner , Ajay Chitnis
DOI: 10.1038/375761A0
关键词:
摘要: X-Delta-1, a Xenopus homologue of the Drosophila Delta gene, is expressed in early embryonic nervous system scattered cells that appear to be prospective primary neurons. Ectopic X-Delta-1 activity inhibits production neurons and interference with endogenous results overproduction These indicate protein mediates lateral inhibition delivered by adjacent cells, commitment neural fate vertebrates regulated Delta-Notch signalling as Drosophila.
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