摘要: For plants, nitrogen is a key nutrient responsible for growth and development. Farms throughout the world rely on fertilizers rich in element to increase production. However, fertilizer use carries high environmental impact, reducing remains challenging goal, especially as global population grows. Uncovering genome-wide regulatory networks that control efficiency has been research focus of Gloria M. Coruzzi, Carroll Milton Petrie Professor Biology at New York University’s (NYU) Center Genomics Systems Biology. Coruzzi also helped develop VirtualPlant (http://virtualplant.bio.nyu.edu/cgi-bin/vpweb/), software platform allows scientists study interaction gene several plant species, including model Arabidopsis thaliana well food crops. PNAS recently spoke who was elected National Academy Sciences 2019, about her current research. Gloria laboratory Image credit: ©Moree; courtesy University Photo Bureau. > PNAS:In your Inaugural Article (1), you demonstrate Michaelis–Menten kinetics, which have used describe kinetics enzymatic reactions, drive plants’ transcriptional response amount received. Why this significant biology, what does discovery mean? > Coruzzi:How organisms sense respond changes dose basic …
scilit.net参考文章(3)
Kenneth A. Johnson, Roger S. Goody, The Original Michaelis Constant: Translation of the 1913 Michaelis–Menten Paper Biochemistry. ,vol. 50, pp. 8264- 8269 ,(2011) , 10.1021/BI201284U
Joseph Swift, Mark Adame, Daniel Tranchina, Amelia Henry, Gloria M. Coruzzi, Water impacts nutrient dose responses genome-wide to affect crop production. Nature Communications. ,vol. 10, pp. 1374- ,(2019) , 10.1038/S41467-019-09287-7
Joseph Swift, Jose M Alvarez, Viviana Araus, Rodrigo A Gutiérrez, Gloria M Coruzzi, Nutrient dose-responsive transcriptome changes driven by Michaelis–Menten kinetics underlie plant growth rates Proceedings of the National Academy of Sciences of the United States of America. ,vol. 117, pp. 12531- 12540 ,(2020) , 10.1073/PNAS.1918619117