Le tissue adipeux: Son rôle dans les maladies métaboliques
作者： J.-P. Pégorier
DOI: 10.1007/978-2-287-33475-7_25
关键词:
摘要: Le tissu adipeux blanc a ete longtemps considere comme un «passif» devolu au stockage et la mobilisation des lipides en reponse signaux hormonaux ou neuronaux. La presence de tres nombreux recepteurs ľinsuline, ľhormone adrenocorticotrope ľadrenaline est accord avec ce concept. Toutefois, decouverte leptine 1994 (1) ľadiponectine 1995 (2) initie reconnaissance tissue organe secretagogue part entiere. Au cours derniere decennie, nombre considerable ďetudes demontre que le secretait nombreuses proteines, peptides facteurs lipidiques agissant facon autocrine, paracrine endocrine, controlant non seulement son activite mais egalement metabolisme energetique dans sa globalite. Ľobjectif chapitre resumer brievement les donnees recentes obtenues domaine, envisageant comment alterations secretion ces proteines changements masse adipeuse (obesite, lipoatrophie⋯) participent developpement complications qui lui sont associees (resistance diabete type 2, risques cardiovasculaires⋯).
springer.com
sci-hub.st 参考文章(101)
Iichiro Shimomura, Robert E. Hammer, Shinji Ikemoto, Michael S. Brown, Joseph L. Goldstein, Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy Nature. ,vol. 401, pp. 73- 76 ,(1999) , 10.1038/43448
David Jablons, Andrew S. Greenberg, Richard P. Nordan, Robert O. Scow, Juan Carlos Calvo, Joseph McIntosh, Interleukin 6 reduces lipoprotein lipase activity in adipose tissue of mice in vivo and in 3T3-L1 adipocytes : a possible role for interleukin 6 in cancer cachexia Cancer Research. ,vol. 52, pp. 4113- 4116 ,(1992)
Claire M. Steppan, Shannon T. Bailey, Savitha Bhat, Elizabeth J. Brown, Ronadip R. Banerjee, Christopher M. Wright, Hiralben R. Patel, Rexford S. Ahima, Mitchell A. Lazar, The hormone resistin links obesity to diabetes Nature. ,vol. 409, pp. 307- 312 ,(2001) , 10.1038/35053000
Takashi Kadowaki, Kazuo Hara, Toshimasa Yamauchi, Yasuo Terauchi, Kazuyuki Tobe, Ryozo Nagai, Molecular mechanism of insulin resistance and obesity. Experimental Biology and Medicine. ,vol. 228, pp. 1111- 1117 ,(2003) , 10.1177/153537020322801003
Delphine Bastelica, Pierre Morange, Bruno Berthet, Hélène Borghi, Odile Lacroix, Michel Grino, Irène Juhan-Vague, Marie-Christine Alessi, Stromal cells are the main plasminogen activator inhibitor-1-producing cells in human fat: evidence of differences between visceral and subcutaneous deposits. Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 22, pp. 173- 178 ,(2002) , 10.1161/HQ0102.101552
Dinesh Khanna, Maureen McMahon, Daniel E. Furst, Anti–tumor necrosis factor α therapy and heart failure: What have we learned and where do we go from here? Arthritis & Rheumatism. ,vol. 50, pp. 1040- 1050 ,(2004) , 10.1002/ART.20164
Takashi Kadowaki, Toshimasa Yamauchi, Adiponectin and Adiponectin Receptors Endocrine Reviews. ,vol. 26, pp. 439- 451 ,(2005) , 10.1210/ER.2005-0005
T. M. Stulnig, W. Waldh�usl, 11β-Hydroxysteroid dehydrogenase Type 1 in obesity and Type 2 diabetes Diabetologia. ,vol. 47, pp. 1- 11 ,(2004) , 10.1007/S00125-003-1284-4
Claire M. Steppan, Mitchell A. Lazar, The current biology of resistin Journal of Internal Medicine. ,vol. 255, pp. 439- 447 ,(2004) , 10.1111/J.1365-2796.2004.01306.X
Gokhan S Hotamisligil, Peter Arner, Jose F Caro, Richard L Atkinson, Bruce M Spiegelman, Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. Journal of Clinical Investigation. ,vol. 95, pp. 2409- 2415 ,(1995) , 10.1172/JCI117936