Export of Bacteriocins

摘要: Bacteriocins are bactericidal proteins that produced by bacteria. They usually kill only bacterial cells closely related to the producing The narrow host range is determined sophisticated uptake mechanisms these use enter susceptible cells. in size from rather small toxic peptides relatively large protein structures of 60–70 kDa. include microcins and lantibiotics (De Vos et al., 1995), most which apparently exported cell via ABC transporters. This chapter will focus on larger bacteriocins, especially colicins cloacin DF13, their mechanism export. These bacteriocins best studied with respect production, export, mode action. Escherichia coli strains gram-negative organisms. translo cated across both inner membrane outer reach extra-cellular destination totally different all other so far. process appears be semi-specific often referred as quasi-lysis. exact not known, but it has been applied for production heterologous E. coli. In this chapter, export biotechnological applications described.