Injury and adaptive mechanisms in skeletal muscle

摘要: Work-related musculoskeletal disorders (MSD) are a major concern in the United States. Overexertion and repetitive motion injuries dominate reporting of lost-time MSD incidents. Over past three decades, there has been much study on contraction-induced skeletal muscle injury. The effect biomechanical loading signature that includes velocity, range motion, number repetitions, force, work-rest cycle, exposure duration studied. More recently, aging injury susceptibility regeneration This review will focus injury, effects cycles, regenerative adaptive pathways. different physiological phenomena responsive to overt versus adaptation be distinguished. inherent capability adapt mechanical loading, given appropriate also discussed. Finally, we submit repeated high-intensity is desirable means attenuate sarcopenia, may most effective appealing mode physical activity counteract often observed with musculo-skeletal dysfunction workplace.