Interpretation of Drug Risk and Benefit: Individual and Population Perspectives
作者： Darrel C Bjornson
DOI: 10.1345/APH.1D401
关键词:
摘要: OBJECTIVETo provide pharmacists with the necessary nomenclature and tools to interpret medical literature on drug risks benefits.DATA SOURCESPrimary articles were identified by MEDLINE search (1990—December 2003) through secondary sources.STUDY SELECTION AND DATA EXTRACTIONAll of from data sources evaluated, all information deemed relevant was included.DATA SYNTHESISArticles in primary reviewed. The show that measurement benefits is consistently reported similar terminology. However, interpretation subsequent balancing can be difficult.CONCLUSIONSAll drugs have concomitant benefits. documents those it this evidence typically used make therapy decisions. Pharmacists who either manage individual patients or populations (pharmacy benefit managers) ma...
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sci-hub.se 参考文章(11)
Yoon Kong Loke, Alastair Bell, Sheena Derry, Aspirin for the prevention of cardiovascular disease: calculating benefit and harm in the individual patient. British Journal of Clinical Pharmacology. ,vol. 55, pp. 282- 287 ,(2003) , 10.1046/J.1365-2125.2003.01774.X
Writing Group for the Women's Health Initiative Investigators, Writing Group for the Women's Health Initiative Investigators, None, Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial JAMA. ,vol. 288, pp. 321- 333 ,(2002) , 10.1001/JAMA.288.3.321
G. Chatellier, E. Zapletal, D. Lemaitre, J. Menard, P. Degoulet, The number needed to treat: a clinically useful nomogram in its proper context. BMJ. ,vol. 312, pp. 426- 429 ,(1996) , 10.1136/BMJ.312.7028.426
C. David Naylor, Measured Enthusiasm: Does the Method of Reporting Trial Results Alter Perceptions of Therapeutic Effectiveness? Annals of Internal Medicine. ,vol. 117, pp. 916- 921 ,(1992) , 10.7326/0003-4819-117-11-916
Lachlan Forrow, William C. Taylor, Robert M. Arnold, Absolutely relative: how research results are summarized can affect treatment decisions. The American Journal of Medicine. ,vol. 92, pp. 121- 124 ,(1992) , 10.1016/0002-9343(92)90100-P
H C Bucher, M Weinbacher, K Gyr, Influence of method of reporting study results on decision of physicians to prescribe drugs to lower cholesterol concentration BMJ. ,vol. 309, pp. 761- 764 ,(1994) , 10.1136/BMJ.309.6957.761
R. J Cook, D. L Sackett, The number needed to treat: a clinically useful measure of treatment effect. BMJ. ,vol. 310, pp. 452- 454 ,(1995) , 10.1136/BMJ.310.6977.452
Jim Nuovo, Reporting Number Needed to Treat and Absolute Risk Reduction in Randomized Controlled Trials JAMA. ,vol. 287, pp. 2813- 2814 ,(2002) , 10.1001/JAMA.287.21.2813
L. S Elting, C. G Martin, S. B Cantor, E. B Rubenstein, Influence of data display formats on physician investigators’ decisions to stop clinical trials: prospective trial with repeated measures BMJ. ,vol. 318, pp. 1527- 1531 ,(1999) , 10.1136/BMJ.318.7197.1527
Sandra J Lewis, Lemuel A Moye, Frank M Sacks, David E Johnstone, Gerald Timmis, Jayne Mitchell, Marian Limacher, Sherron Kell, Stephen P Glasser, Jane Grant, Barry R Davis, Marc A Pfeffer, Eugene Braunwald, Effect of Pravastatin on Cardiovascular Events in Older Patients with Myocardial Infarction and Cholesterol Levels in the Average Range: Results of the Cholesterol and Recurrent Events (CARE) Trial Annals of Internal Medicine. ,vol. 129, pp. 681- 689 ,(1998) , 10.7326/0003-4819-129-9-199811010-00002