Oxygen transport in the critically ill patient

作者: Christopher W. Bryan-Brown

DOI: 10.1016/S0950-3501(05)80056-X

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摘要: Summary The traditional view of oxygen transport as the product haemoglobin, oxygenation and cardiac output holds up well, but because efficiency delivery (the extraction ratio) is sometimes a fixed parameter in critically ill, absolute values for each determinant are difficult to define seem have large range adequate function. main factor effective tissues when limited. In most acute circumstances blood volume not easy estimate without direct measurement. Hypovolaemia may influence distribution unfavourably away from splanchnic renal circulations. Monitoring variables be indirect, looking at compensations inadequate delivery, such comparing transcutaneous tension arterial tension, intramural gastric pH or lactate concentrations. monitoring uptake can done with conventional intensive care unit (cardiac output, mixed venous gases). airway measurement also includes pulmonary utilization, which high ARDS pneumonia. Prehospital emergency management should maintain volume, aim reduce additional burdens pain, agitation shivering. This then developed into full critical therapy department. chief priority any department develop organization protocols maximize survival.

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