Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation.

作者: Mhairi J. Maxwell , Erik Westein , Warwick S. Nesbitt , Simon Giuliano , Sacha M. Dopheide

DOI: 10.1182/BLOOD-2006-07-028282

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摘要: … (D) Platelets within the superficial layer of thrombi were loosely packed such that platelets often detached from the thrombus surface in clusters (Video S2). White scale bar = 5 μM; black …

参考文章(55)
Zaverio M Ruggeri, Mechanisms initiating platelet thrombus formation. Thrombosis and Haemostasis. ,vol. 78, pp. 611- 616 ,(1997) , 10.1055/S-0038-1657598
Abby R Saniabadi, Kazuo Umemura, Nobuteru Matsumoto, Sadayuki Sakuma, Mitsuyoshi Nakashima, Vessel wall injury and arterial thrombosis induced by a photochemical reaction. Thrombosis and Haemostasis. ,vol. 73, pp. 868- 872 ,(1995) , 10.1055/S-0038-1653883
Renata Polanowska-Grabowska, Carl G Simon Jr, Adrian RL Gear, None, Platelet adhesion to collagen type I, collagen type IV, von Willebrand factor, fibronectin, laminin and fibrinogen: rapid kinetics under shear. Thrombosis and Haemostasis. ,vol. 81, pp. 118- 123 ,(1999) , 10.1055/S-0037-1614428
Graham C.R. Ellis-Davies, Development and application of caged calcium. Methods in Enzymology. ,vol. 360, pp. 226- 238 ,(2003) , 10.1016/S0076-6879(03)60112-6
S M Schoenwaelder, S P Jackson, Y Yuan, M S Teasdale, H H Salem, C A Mitchell, Tyrosine kinases regulate the cytoskeletal attachment of integrin alpha IIb beta 3 (platelet glycoprotein IIb/IIIa) and the cellular retraction of fibrin polymers. Journal of Biological Chemistry. ,vol. 269, pp. 32479- 32487 ,(1994) , 10.1016/S0021-9258(18)31660-0
MH Kroll, JD Hellums, LV McIntire, AI Schafer, JL Moake, Platelets and shear stress. Blood. ,vol. 88, pp. 1525- 1541 ,(1996) , 10.1182/BLOOD.V88.5.1525.1525
Shaun P. Jackson, Simone M. Schoenwaelder, Antiplatelet therapy: in search of the 'magic bullet'. Nature Reviews Drug Discovery. ,vol. 2, pp. 775- 789 ,(2003) , 10.1038/NRD1198
J.-Y. Shao, H. P. Ting-Beall, R. M. Hochmuth, Static and dynamic lengths of neutrophil microvilli Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 6797- 6802 ,(1998) , 10.1073/PNAS.95.12.6797
Bernhard Nieswandt, Steve P. Watson, Platelet-collagen interaction: is GPVI the central receptor? Blood. ,vol. 102, pp. 449- 461 ,(2003) , 10.1182/BLOOD-2002-12-3882