Comorbidity and polypharmacy in elderly cancer patients: The significance on treatment outcome and tolerance
作者： Trine Lembrecht Jørgensen , Jesper Hallas , Lotte Holm Land , Jørn Herrstedt
DOI: 10.1016/J.JGO.2010.06.003
关键词:
摘要: Abstract Older adults have an increased burden of comorbidity which increases their risk being exposed to polypharmacy. Because underrepresentation elderly cancer patients in clinical trials, knowledge the influence and polypharmacy on these patients' response tolerance antineoplastic treatment is sparse. We reviewed literature impact factors outcome. Large population-based studies all found association between survival among patients. However, we need focus cancer-specific conclude disease its treatment. Prospective are needed
elsevier.com
core.ac.uk 
sci-hub.se 参考文章(106)
ME Corcoran, Polypharmacy in the Older Patient With Cancer. Cancer Control. ,vol. 4, pp. 419- 428 ,(1997)
Lodovico Balducci, Aging, frailty, and chemotherapy. Cancer Control. ,vol. 14, pp. 7- 12 ,(2007) , 10.1177/107327480701400102
Christopher M Booth, Anil Joy, Mark Clemons, Scott Young, Maureen Trudeau, Walter Callaghan, Teresa Petrella, George Dranitsaris, Chemotherapy-induced nausea and vomiting in breast cancer patients: a prospective observational study. The journal of supportive oncology. ,vol. 5, pp. 374- 380 ,(2007)
Prevention of chemotherapy- and radiotherapy-induced emesis: Results of the 2004 Perugia International Antiemetic Consensus Conference Annals of Oncology. ,vol. 17, pp. 20- 28 ,(2006) , 10.1093/ANNONC/MDJ078
David Solomon, A. Sue Brown, Kenneth Brummel-Smith, Lavola Burgess, Ralph B. D'Agostino, John W. Goldschmidt, Jeffrey B. Halter, William R. Hazzard, Dennis W. Jahnigen, Charles Phelps, Murray Raskind, Robert W. Schrier, Harold C. Sox, Sankey V. Williams, May Wykle, Best Paper of the 1980s: National Institutes of Health Consensus Development Conference Statement: Geriatric Assessment Methods for Clinical Decision‐Making Journal of the American Geriatrics Society. ,vol. 51, pp. 1490- 1494 ,(2003) , 10.1046/J.1532-5415.2003.51471.X
Julia Bohlius, Kurt Schmidlin, Corinne Brillant, Guido Schwarzer, Sven Trelle, Jerome Seidenfeld, Marcel Zwahlen, Mike J Clarke, Olaf Weingart, Sabine Kluge, Margaret Piper, Maryann Napoli, Dirk Rades, David Steensma, Benjamin Djulbegovic, Martin F Fey, Isabelle Ray-Coquard, Volker Moebus, Gillian Thomas, Michael Untch, Martin Schumacher, Matthias Egger, Andreas Engert, Erythropoietin or Darbepoetin for patients with cancer--meta-analysis based on individual patient data. Cochrane Database of Systematic Reviews. ,vol. 2009, ,(2009) , 10.1002/14651858.CD007303.PUB2
Giuseppe De Cataldis, Annunziato Iannelli, Domenico Bilancia, Mario Belli, Bruno Massidda, Francovito Piantedosi, Giuseppe Comella, Mario De Lena, Giuseppe Frasci, Vito Lorusso, Nicola Panza, Pasquale Comella, Gianpaolo Nicolella, Andrea Bianco, Gemcitabine Plus Vinorelbine Versus Vinorelbine Alone in Elderly Patients With Advanced Non–Small-Cell Lung Cancer Journal of Clinical Oncology. ,vol. 18, pp. 2529- 2536 ,(2000) , 10.1200/JCO.2000.18.13.2529
F Di Costanzo, L Patoia, F Roila, M Tonato, C Basurto, M Picciafuoco, S Bracarda, D Donati, P Malacarne, L Monici, Protection from nausea and vomiting in cisplatin-treated patients: high-dose metoclopramide combined with methylprednisolone versus metoclopramide combined with dexamethasone and diphenhydramine: a study of the Italian Oncology Group for Clinical Research. Journal of Clinical Oncology. ,vol. 7, pp. 1693- 1700 ,(1989) , 10.1200/JCO.1989.7.11.1693
Martin Nuttall, Jan van der Meulen, Mark Emberton, Charlson scores based on ICD-10 administrative data were valid in assessing comorbidity in patients undergoing urological cancer surgery Journal of Clinical Epidemiology. ,vol. 59, pp. 265- 273 ,(2006) , 10.1016/J.JCLINEPI.2005.07.015
Renata Marinello, Daniela Marenco, Daniela Roglia, Maria Francesca Stasi, Alberto Ferrando, Manuela Ceccarelli, Oscar Bertetto, Mario Molaschi, Giovannino Ciccone, Predictors of treatment failures during chemotherapy: A prospective study on 110 older cancer patients. Archives of Gerontology and Geriatrics. ,vol. 48, pp. 222- 226 ,(2009) , 10.1016/J.ARCHGER.2008.01.011