Effect of Paralysis at the Time of ProSeal Laryngeal Mask Airway Insertion on Pharyngolaryngeal Morbidities. A Randomized Trial

摘要: Neuromuscular block results in the loss of muscular tone upper airway, which might contribute to increased postoperative airway morbidity followed by ProSeal laryngeal mask (PLMA) insertion. We compared pharyngolaryngeal discomfort exerted PLMA according neuromuscular block. One hundred sixty patients undergoing surgery for breast disease or inguinal hernia were anesthetized with propofol and remifentanil target controlled infusion. Rocuronium 0.6 mg/kg (NMBA group, n = 80) normal saline (No-NMBA was administered after consciousness, one anesthesiologist inserted PLMA. Postoperative evaluated at 1 h. Traumatic event recorded based on blood trace surface cuff. Insertion time, insertion attempt number, sealing pressure, fiberoptic brochoscopic grades evaluated. Patients’ characteristics condition (insertion successful bronchoscopic grade, pressure) similar between two groups. The can be successfully non-paralyzed less than when a blocking agent is used (13.8% vs. 30.0%, P 0.021). incidence traumatic events also reduced no (16.3% 32.5%, 0.026). Regardless whether not surgical procedure requires relaxation, there need administer agents solely purpose insertion. Trial Registration ClinicalTrials.gov NCT01035021