Tcl1 enhances akt kinase activity and mediates its nuclear translocation
作者： Yuri Pekarsky , Carlo Croce
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摘要: The TCL1 oncogene at 14q32.1 is involved in the development of human leukemia. This invention demonstrates interaction between Tcl1 and Akt1 proteins. physical endogenous occurs through PH domain protein. present relates to identification mimics antagonists that modifying this interaction, with subsequent modification apoptotic proliferative signals.
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lens.org 参考文章(18)
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