Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

作者: Ellen M. Sletten , Carolyn R. Bertozzi

DOI: 10.1002/ANIE.200900942

关键词:

摘要: … We have exploited the FGE consensus as a genetically encoded aldehyde tag for site-… with a triarylphosphine and quantifying the amount of free sulfhydryl groups on the cell surface by …

参考文章(338)
Rolf Huisgen, 1,3-Dipolar Cycloadditions. Past and Future† Angewandte Chemie. ,vol. 2, pp. 565- 598 ,(1963) , 10.1002/ANIE.196305651
D. Summerer, S. Chen, N. Wu, A. Deiters, J. W. Chin, P. G. Schultz, A Genetically Encoded Fluorescent Amino Acid Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 9785- 9789 ,(2006) , 10.1073/PNAS.0603965103
P. Wu, W. Shui, B. L. Carlson, N. Hu, D. Rabuka, J. Lee, C. R. Bertozzi, Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag Proceedings of the National Academy of Sciences of the United States of America. ,vol. 106, pp. 3000- 3005 ,(2009) , 10.1073/PNAS.0807820106
James V. Staros, Hagan Bayley, David N. Standring, Jeremy R. Knowles, Reduction of aryl azides by thiols: Implications for the use of photoaffinity reagents Biochemical and Biophysical Research Communications. ,vol. 80, pp. 568- 572 ,(1978) , 10.1016/0006-291X(78)91606-6
Neal K. Devaraj, Ralph Weissleder, Scott A. Hilderbrand, Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjugate Chemistry. ,vol. 19, pp. 2297- 2299 ,(2008) , 10.1021/BC8004446
Howard C. Hang, Ernst-Jan Geutjes, Gijsbert Grotenbreg, Annette M. Pollington, Marie Jose Bijlmakers, Hidde L. Ploegh, Chemical probes for the rapid detection of Fatty-acylated proteins in Mammalian cells. Journal of the American Chemical Society. ,vol. 129, pp. 2744- 2745 ,(2007) , 10.1021/JA0685001
Eliana Saxon, Carolyn R Bertozzi, Cell Surface Engineering by a Modified Staudinger Reaction Science. ,vol. 287, pp. 2007- 2010 ,(2000) , 10.1126/SCIENCE.287.5460.2007
Jan C. M. van Hest, Kristi L. Kiick, David A. Tirrell, Efficient incorporation of unsaturated methionine analogues into proteins in vivo Journal of the American Chemical Society. ,vol. 122, pp. 1282- 1288 ,(2000) , 10.1021/JA992749J
Anna E. Speers, Benjamin F. Cravatt, Chemical strategies for activity-based proteomics. ChemBioChem. ,vol. 5, pp. 41- 47 ,(2004) , 10.1002/CBIC.200300721
Christian P. R. Hackenberger, Dirk Schwarzer, Chemoselective Ligation and Modification Strategies for Peptides and Proteins Angewandte Chemie. ,vol. 47, pp. 10030- 10074 ,(2008) , 10.1002/ANIE.200801313