Method for identification of target genes of transcription factors

作者: Alain Prochiantz , Wolfgang Wurst

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摘要: Transcription factor responsive elements, target genes, and co-factors of a transcription factor, either individually or in combination, are identified by integrating into the genome eukaryotic cell gene trap vector that includes reporter gene, polyadenylation site, selectable marker selecting cells which is successfully integrated contacting those with then identifying cultivating having has been activity altered interaction between element element, cofactor interacts factor.

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