Recent advances in managing Peyronie’s disease

作者: Oliver Kayes , Rauf Khadr

DOI: 10.12688/F1000RESEARCH.9041.1

关键词:

摘要: Peyronie’s disease remains an under-reported and debilitating problem which can result in significant physical psychological symptoms for some men. The classic symptom complex includes penile curvature, plaque, pain. Men also present with erectile dysfunction, instability, shortening, alongside feelings of low mood/libido, dysmorphobia, self-esteem. This review highlights the current key publications medical literature provides updates on new clinical therapies whilst postulating about potential future treatments horizon.

参考文章(67)
Carrie A. Stewart, Faysal A. Yafi, Margaret Knoedler, Sree H. Mandava, Ian R. McCaslin, Premsant Sangkum, Suresh Sikka, Landon Trost, Wayne J.G. Hellstrom, Intralesional Injection of Interferon-α2b Improves Penile Curvature in Men with Peyronie's Disease Independent of Plaque Location. The Journal of Urology. ,vol. 194, pp. 1704- 1707 ,(2015) , 10.1016/J.JURO.2015.06.096
Romano Gennaro, Davide Barletta, Gianni Paulis, Intralesional hyaluronic acid: an innovative treatment for Peyronie’s disease International Urology and Nephrology. ,vol. 47, pp. 1595- 1602 ,(2015) , 10.1007/S11255-015-1074-1
James P. Tursi, David J. Ralph, Laurence A. Levine, Beatrice Cuzin, Stephen Mark, Martin K. Gelbard, Nigel A. Jones, Genzhou Liu, Gregory J. Kaufman, Clinical Safety and Effectiveness of Collagenase Clostridium Histolyticum Injection in Patients With Peyronie's Disease: A Phase 3 Open-Label Study The Journal of Sexual Medicine. ,vol. 12, pp. 248- 258 ,(2015) , 10.1111/JSM.12731
Ahmet Gokce, Zakaria Y. Abd Elmageed, George F. Lasker, Mostafa Bouljihad, Stephen E. Braun, Hogyoung Kim, Philip J. Kadowitz, Asim B. Abdel‐Mageed, Suresh C. Sikka, Wayne J. Hellstrom, Intratunical Injection of Genetically Modified Adipose Tissue‐Derived Stem Cells with Human Interferon α‐2b for Treatment of Erectile Dysfunction in a Rat Model of Tunica Albugineal Fibrosis The Journal of Sexual Medicine. ,vol. 12, pp. 1533- 1544 ,(2015) , 10.1111/JSM.12916
Mohammad Reza Safarinejad, Majid Ali Asgari, Seyyed Yousof Hosseini, Farid Dadkhah, A double‐blind placebo‐controlled study of the efficacy and safety of pentoxifylline in early chronic Peyronie’s disease BJUI. ,vol. 106, pp. 240- 248 ,(2009) , 10.1111/J.1464-410X.2009.09041.X
Martin K. Gelbard, Frederick Dorey, Kathleen James, The Natural History of Peyronie’s Disease Journal of Urology. ,vol. 144, pp. 1376- 1379 ,(1990) , 10.1016/S0022-5347(17)39746-X
Georgios Hatzichristodoulou, Christoph Meisner, Jürgen E. Gschwend, Arnulf Stenzl, Sven Lahme, Extracorporeal shock wave therapy in Peyronie's disease: results of a placebo-controlled, prospective, randomized, single-blind study. The Journal of Sexual Medicine. ,vol. 10, pp. 2815- 2821 ,(2013) , 10.1111/JSM.12275
Laurence A. Levine, Stephen M. Larsen, Surgical Correction of Persistent Peyronie's Disease Following Collagenase Clostridium Histolyticum Treatment The Journal of Sexual Medicine. ,vol. 12, pp. 259- 264 ,(2015) , 10.1111/JSM.12721
Michael R. Abern, Stephen Larsen, Laurence A. Levine, Combination of Penile Traction, Intralesional Verapamil, and Oral Therapies for Peyronie's Disease The Journal of Sexual Medicine. ,vol. 9, pp. 288- 295 ,(2012) , 10.1111/J.1743-6109.2011.02519.X