Comparison of the DNA content in liver cell adenoma, hepatocellular carcinoma and regenerative nodules.

摘要: With regard to neoplasms of hepatocytes, diagnostic pitfalls have been reported for differentiation liver cell adenoma (LCA) from well differentiated hepatocellular carcinoma (HCC). Since cytophotometric analysis the DNA content with help image has proven be value in various neoplasms, we examined its ability discriminate between LCA and HCC as regenerative nodules. The material investigated consisted 54 cases HCC, 10 benign tumours suspicious HCC. All demonstrated an euploid histogram. 9 out borderline were while 1 was suspiciously aneuploid. Among 21 euploid, 18 15 clearly 5c exceeding rate differed significantly changes lesions (p = 0.0474) malignant 0.0108). We conclude that use cytometry is helpful additional criterion more accuracy morphologically difficult cases.