Influences of antihypertensive and antihyperlipidemic drugs on the senses of taste and smell: a review.

作者: Richard L Doty , Shaji Philip , Krishna Reddy , Kara-Lynne Kerr

DOI: 10.1097/00004872-200310000-00003

关键词:

摘要: According to the Physicians' Desk Reference (PDR), 36% of modern antihypertensive and antihyperlipidemic drugs produce untoward alterations in chemosensory perception. Such disturbances can adversely affect quality life, non-compliance medication schedules, may result decreased food intake, loss appetite, weight decrement, depression. This review lists primary that alter function, provides information on better defining nature dysfunction, outlines testing strategies available tests could be used define prevalence summarizes means for mitigating such alterations.

参考文章(37)
J.A. Maruniak, W.L. Silver, D.G. Moulton, Olfactory receptors respond to blood-borne odorants Brain Research. ,vol. 265, pp. 312- 316 ,(1983) , 10.1016/0006-8993(83)90348-7
R. Doty, P Shaman, S. Applebaum, R Giberson, L Siksorski, L Rosenberg, Smell identification ability: changes with age Science. ,vol. 226, pp. 1441- 1443 ,(1984) , 10.1126/SCIENCE.6505700
AlexanderA Bachmanov, Gunther Schlager, MichaelG Tordoff, GaryK Beauchamp, Consumption of electrolytes and quinine by mouse strains with different blood pressures1 Physiology & Behavior. ,vol. 64, pp. 323- 330 ,(1998) , 10.1016/S0031-9384(98)00069-9
Richard D. Mattes, Karl Engelman, Effects of combined hydrochlorothiazide and amiloride versus single drug on changes in salt taste and intake The American Journal of Cardiology. ,vol. 70, pp. 91- 95 ,(1992) , 10.1016/0002-9149(92)91396-L
Ian Boyd, CAPTOPRIL-INDUCED TASTE DISTURBANCE The Lancet. ,vol. 342, pp. 304- 304 ,(1993) , 10.1016/0140-6736(93)91850-L
J J McNeil, A Anderson, N Christophidis, B Jarrott, W J Louis, Taste loss associated with captopril treatment. BMJ. ,vol. 2, pp. 1555- 1556 ,(1979) , 10.1136/BMJ.2.6204.1555-A
Satoshi Morimoto, Martin D. Cassell, Curt D. Sigmund, Glia- and neuron-specific expression of the renin-angiotensin system in brain alters blood pressure, water intake, and salt preference. Journal of Biological Chemistry. ,vol. 277, pp. 33235- 33241 ,(2002) , 10.1074/JBC.M204309200
Bradley K. Formaker, David L. Hill, Peripheral taste responses in genetically hypertensive rats Physiology & Behavior. ,vol. 47, pp. 1229- 1237 ,(1990) , 10.1016/0031-9384(90)90376-F