作者: MichaelD. Brundage , JosephL. Pater , Dongsheng Tu , Michael Palmer , Andrea Bezjak
DOI: 10.1016/S0149-2918(02)85103-7
关键词:
摘要: 0.001). The majority of participants were males (83%) who had been treated with primary radiotherapy (97%) for stage I disease (53%) the glottis (75%), and 7% undergone total laryngectomy. Among participants, average FACT-HN TTO: r = 0.216, P c 95% CI, 0%-11%) 0.06/1.00 (6%; 0%-10%). Similar results found Karnofsky performance status instrument, DATE utility most subscales FACT-H&N. These “positive” “negative” estimates MID statistically different (P < DISCUSSION: Cancer survivors may be more sensitive to favorable than unfavorable differences in wellbeing. This suggests that small improvements important, but decrements similar magnitude below threshold detection individual patients. A review previous publications showed MIDs smaller 4 studies. CONCLUSIONS: across instruments diseases, values remain constant at -5% 10% instrument range. It eventually possible estimate a new by generalizing these findings, avoiding necessity conducting studies each or patient population. ACKNOWLEDGMENT: work was carried out as part Master’s thesis, portions have published previously.