Transvenous lead extraction in patients with cardiac resynchronization therapy devices is not associated with increased 30-day mortality.

作者: Justin Gould , Magdalena Klis , Bradley Porter , Benjamin J Sieniewicz , Baldeep S Sidhu

DOI: 10.1093/EUROPACE/EUY290

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摘要: AIMS Transvenous lead extraction (TLE) may be necessary due to system infection/erosion or malfunction. Cardiac resynchronization therapy (CRT) patients undergoing TLE at greater risk increased comorbidities. We examined whether with CRT systems had more comorbidities and higher 30-day mortality than those non-CRT devices. METHODS AND RESULTS All TLEs between October 2000 December 2016 were prospectively collected. During this period 925 occurred (CRT group 231, 694). older (68.1 ± 10.8 years vs. 64.3 ± 16.1 years, P = 0.024); likely male (85.7% 69%, P < 0.001); lower mean left ventricular ejection fraction (34.1 ± 12.7% 48.3 12.9%, prevalence of renal impairment (33.8% 13.7%, P < 0.001) have ≥2 (84% 40.1%, P < 0.001). Mean dwell time was in the (5.6 ± 5.5 years 7.6 ± 7.1 years, P = 0.002). There no significant difference all-cause rates (3.0%, n = 7) (2.0%, n = 14) (P = 0.443). The majority deaths both groups sepsis. Univariate multivariate analysis showed age, sepsis associated mortality. a did not predict CONCLUSION when compared patients. Age, independent predictors Sepsis main cause

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