Renal function, aldosterone, and vasopressin excretion following repeated long-distance running

摘要: Renal and endocrine responses were studied in 10 male runners during a 20-day 500-km race. Overnight urine prerun blood samples taken prior to running on days 1, 2, 5, 8, 14, 17, 20. Day 13 followed 70 h of rest. Urine flow rate, osmotic clearance, tubular free water reabsorption, urinary vasopressin excretion body weight not significantly changed. Creatinine clearance was constant except for an elevation day 5. Plasma osmolality elevated 17. sodium increased (P less than 0.05) 2 but reduced The percentage filtered excreted all nights following recovery 13. Urinary aldosterone rate 162, 117, 97% 20 returned control levels after These data suggest that response repeated long-distance normal fluid balance is regained within 12 h. However, it necessary conserve at least 24 exercise as evidenced by the decrease percent continued excretion.