作者: Mark F. McCarty , Jorge Barroso-Aranda , Francisco Contreras
DOI: 10.1016/J.MEHY.2008.09.060
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摘要: Recent studies show that ingestion of flavanol-rich cocoa powder provokes increased endothelial production nitric oxide - an effect likely mediated by epicatchin and thus may have considerable potential for promoting vascular health. The Kuna Indians Panama, who regularly consume large amounts cocoa, are virtually free hypertension stroke, even though they salt their food. Of potentially complementary merit is the cyanobacterium spirulina, which has been used as a food in certain cultures. Spirulina exceptionally rich phycocyanobilin (PCB), recently shown to act potent inhibitor NADPH oxidase; this rationalizes broad range anti-inflammatory, cytoprotective, anti-atherosclerotic effects orally administered spirulina achieved rodent studies. In light central pathogenic role oxidase-derived oxidant stress plays vast disorders, or PCB-enriched extracts remarkable preserving restoring Joint administration particular merit, inasmuch can mask somewhat disagreeable flavor odor whereas antioxidant impact could be expected amplify bioactivity evoked flavanols inflamed endothelium. Moreover, there reason suspect that, optimizing cerebrovascular perfusion while quelling cerebral stress, collaborate prevention senile dementia. Thus, products featuring ample both high-flavanol health promotion, evaluation clinical trials.