The buccale puzzle: The symbiotic nature of endogenous infections of the oral cavity.

摘要: The indigenous, 'normal', microflora causes the majority of localized infectious diseases oral cavity (eg, dental caries, alveolar abscesses, periodontal and candidiasis). same also protects host from exogenous pathogens by stimulating a vigorous immune response provides colonization resistance. How can that supports health cause endogenous disease? This paradoxical host-symbiont relationship will be discussed within dynamic symbiosis.Symbiosis means 'life together' - it is capable continuous change as determined selective pressures milieu. Mutualistic symbiosis, where both indigenous benefit association, may shift to parasitic damaged benefit. Importantly, these are reversible relationships. microbial dynamism, called amphibiosis, essential adaptive process determines causation disease or maintenance mutualistic microflora.Complex consortiums, existing biofilm, usually provide interfaces initiate perpetuate assault on tissue. ecology various microhabitats critical for development appropriate selecting milieux pathogens. microbiota associated with caries progression primarily influenced prevailing pH, whereas pulpal infection appear more dependent redox potential. Candidiasis results factors favour yeast overgrowth bacterial suppression caused antibiotics. Oral an adventitious event adaptation conditions; prevention occur only when we realize heart