Is survival reduced for patients with anal cancer requiring surgery after failure of radiation? Analysis from a population study over two decades.

摘要: Chemoradiotherapy is the standard treatment for anal cancer. Surgery reserved failure of therapy, but there are limited data examining outcomes after surgery. From a prospective population-based database on radiation and surgical we compare patients with cancer undergoing rectal resection alone. Patients rectum initial (SRT) squamous cell carcinoma anus, canal, cloacogenic zone, overlapping lesions canal from 1983 to 2002 were identified Surveillance, Epidemiology End Results database. Patient tumor characteristics SRT compared those who underwent alone (RT). Survival was calculated by Kaplan-Meier test. There 1202 RT 48 SRT. had similar median age, gender, grade tumor. more regional stage disease (66.7 vs 42.4%, P = 0.001). Mean survival was, however, (103 96 months, 0.8). For localized stage, (105 98 0.7). (95 83 0.6). The presence appears be associated radiotherapy. such comparable that Because combined chemotherapy, this suggests salvage surgery therapy results in combination