摘要: Many subtypes in malignant lymphoma, especially those of B-cell lineage, have been established by linking morphologically each them to one the normal lymphoid development stages. Recent researches justified some entities terms clinical aspects and biological natures. Moreover, new techniques findings immunology settled many problems disease which had unsolved conventional ones. Single cell analysis on somatic hypermutation, for instance, shed light nature Hodgkin's disease. A good knowledge lymphocyte makes it easier understand is very important hematologists hematopathologists dealing with Development tissue recent advances this field will be briefly reviewed.