How stress contributes to autoimmunity-lessons from Sjögren's syndrome

作者: Fotini N Skopouli , Stergios Katsiougiannis , None

DOI: 10.1002/1873-3468.12933

关键词:

摘要: A large body of clinical evidence on the association between stressful life events and autoimmune diseases suggests that stress may play an important role in pathogenesis these disorders. In this article, we discuss effects stress, not immune system but specific cell populations against which reactivity is directed. Using Sjogren's syndrome as a model disease, review initiation perpetuation reactivity. We present data reveal salivary gland epithelial cells, suggesting can become immunogenic through its various epithelium.

参考文章(73)
Yehuda Shoenfeld, Gisele Zandman-Goddard, Ljudmila Stojanovich, Maurizio Cutolo, Howard Amital, Yair Levy, Mahmoud Abu-Shakra, Ori Barzilai, Yackov Berkun, Miri Blank, JF de Carvalho, Andrea Doria, Boris Gilburd, Uriel Katz, Ilan Krause, Pnina Langevitz, Hedi Orbach, Vitor Pordeus, Maya Ram, Elias Toubi, Yaniv Sherer, None, The mosaic of autoimmunity: hormonal and environmental factors involved in autoimmune diseases--2008. Israel Medical Association Journal. ,vol. 10, pp. 8- 12 ,(2008)
Anne Bertolotti, Yuhong Zhang, Linda M. Hendershot, Heather P. Harding, David Ron, Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response Nature Cell Biology. ,vol. 2, pp. 326- 332 ,(2000) , 10.1038/35014014
Victoria L. Crotzer, Janice S. Blum, Autophagy and Its Role in MHC-Mediated Antigen Presentation Journal of Immunology. ,vol. 182, pp. 3335- 3341 ,(2009) , 10.4049/JIMMUNOL.0803458
Ali M. Komai, Cecilia Brännmark, Saliha Musovic, Charlotta S. Olofsson, PKA-independent cAMP stimulation of white adipocyte exocytosis and adipokine secretion: modulations by Ca2+ and ATP The Journal of Physiology. ,vol. 592, pp. 5169- 5186 ,(2014) , 10.1113/JPHYSIOL.2014.280388
Takaaki Inaba, Chihiro Hisatsune, Yasumasa Sasaki, Yoko Ogawa, Etsuko Ebisui, Naoko Ogawa, Minoru Matsui, Tsutomu Takeuchi, Katsuhiko Mikoshiba, Kazuo Tsubota, Mice Lacking Inositol 1,4,5-Trisphosphate Receptors Exhibit Dry Eye PLoS ONE. ,vol. 9, pp. e99205- ,(2014) , 10.1371/JOURNAL.PONE.0099205
Theocharis Panaretakis, Oliver Kepp, Ulf Brockmeier, Antoine Tesniere, Ann-Charlotte Bjorklund, Daniel C Chapman, Michael Durchschlag, Nicholas Joza, Gérard Pierron, Peter van Endert, Junying Yuan, Laurence Zitvogel, Frank Madeo, David B Williams, Guido Kroemer, Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death The EMBO Journal. ,vol. 28, pp. 578- 590 ,(2009) , 10.1038/EMBOJ.2009.1
Shen Hu, Kai Gao, Rodney Pollard, Martha Arellano‐Garcia, Hui Zhou, Lei Zhang, David Elashoff, Cees GM Kallenberg, Arjan Vissink, David T Wong, None, Preclinical validation of salivary biomarkers for primary Sjögren's syndrome Arthritis Care & Research. ,vol. 62, pp. 1633- 1638 ,(2010) , 10.1002/ACR.20289
Xieyi Cai, Lingyan Zheng, Chuangqi Yu, Zhiyuan Zhang, Chi Yang, Expression of interferon regulatory factor 1, 3, and 7 in primary Sjögren syndrome Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. ,vol. 107, pp. 661- 668 ,(2009) , 10.1016/J.TRIPLEO.2009.01.039
Hristina Ivanova, Tim Vervliet, Ludwig Missiaen, Jan B. Parys, Humbert De Smedt, Geert Bultynck, Inositol 1,4,5-trisphosphate receptor-isoform diversity in cell death and survival Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. ,vol. 1843, pp. 2164- 2183 ,(2014) , 10.1016/J.BBAMCR.2014.03.007