作者: Michael Brenner , Albee Messing
DOI: 10.1007/978-1-4939-0974-2_5
关键词:
摘要: Alexander disease is a protein aggregation disorder resulting from mutations in the intermediate filament protein, GFAP. Progress past 15 years has defined numerous aspects of astrocyte function that are impacted by these mutations, and might be amenable to correction. Since reversal dysfunction likely valuable wide variety conditions, offers unique opportunities for exploring newly emerging field astrotherapeutics.