摘要: Due to the complexity of organization and function human brain, a large proportion (estimates are >50%) 40 000 or so genes in genome expected be involved formation brain [20]. As hydrocephalus is frequent manifestation variety neurological diseases, we at threshold for improved understanding molecular pathogenesis its associated diseases. This review discusses genetics CNS disorders with hydrocephalus. In these usually not only clinical genetic defect, but seen context more broad malformation syndrome. this Chapter I intend focus on that have been significantly characterized from studies subjects animal models. These studies, mainly using mice, led exciting discoveries will prove breakthroughs many
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