Inflammatory lesions of the human placenta. III: The histopathology of villitis of unknown aetiology

摘要: All placentae delivered in a large obstetrics hospital two-year period were examined macroscopically and histologically. Of 7505 consecutive singleton placentae, chronic focal placental villitis of unknown aetiology (VUE) was found 575 (7.6 per cent). The clinical correlates these cases have been published previously (Russell, 1979). present report details histological spectra severity distribution the lesions, cell types within inflammatory foci secondary changes consequent upon local reduction both maternal fetal blood flow through placenta. Histological findings tend to support direct extension infection from uterine sources rather than haematogenous inoculation sequelae for infant appear correlate positively with process.