Method to estimate age of individual based on epigenetic markers in biological sample
作者： Eric Vilain , Sven Bocklandt , Steve Horvath , Janet Sinsheimer
DOI:
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摘要: The invention provides methods and materials that use observation of DNA characteristics to obtain information relating the age individuals. instant disclosure identifies 88 sites in or near 80 genes for which degree cytosine methylation epithelial and/or white blood cells is significantly correlated with age. In illustrative embodiments invention, patterns promoters EDARADD, TOMILI, NPTX2 are used predict an individual a high accuracy.
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