Total synthesis of 11-R,12-R-dihydroxyeicosatrienoic acid, a metabolite of the cytochrome P-450 epoxygenase pathway
作者： Steven S. Wang , Joshua Rokach
DOI: 10.1016/S0040-4039(00)73401-0
关键词:
摘要: The first total and enantioselective synthesis of 11-R,12-R-dihydroxy-5,8,14-eicosatrienoic acid 7 is reported. We have used the carbohydrate 2-deoxy-D-glucose as a masked 1,6-dialdehyde precursor 20 to perform synthesis. availability this material will allow, among other things, testing hypothesis that it can be biochemical 12-R-HETE in vivo.
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sci-hub.se 参考文章(12)
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