Azidomethyl ether deprotection method

作者: Gordon Mcinroy , Radu Lazar , Michael C Chen , Jiahao Huang

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摘要: The invention relates to a method of converting an azidomethyl ether substituent free hydroxyl group. also tomethods nucleic acid synthesis and sequencing comprising the use nucleotide triphosphates having 3'-O-azidomethyl substituent, kitscomprising photoactivatable transition metal complex said kits in methods sequencing.

参考文章(18)
Kai Wu, Xing Su, David J. Liu, Nucleic acid sequencing and electronic detection ,(2008)
Sylvestre Bonnet, Light induced drug release ,(2011)
Xiaohai Liu, Mark Smith, John Milton, Silke Ruediger, Joseph Brennan, Colin Barnes, Xiaolin Wu, Modified nucleotides for polynucleotide sequencing ,(2003)
Xin-Ming Liu, Richard A. Reinhardt, Dong Wang, Drug carriers, their synthesis, and methods of use thereof ,(2007)
Kazuhiro Furukawa, Hiroshi Abe, Satoshi Tsuneda, Yoshihiro Ito, Photoactivatable fluorescein derivatives with azidomethyl caging groups for tracing oligonucleotides in living human cells Organic and Biomolecular Chemistry. ,vol. 8, pp. 2309- 2311 ,(2010) , 10.1039/B926100A
Bernard Loubinoux, Samir Tabbache, Philippe Gerardin, Joseph Miazimbakana, Protection des phenols par le groupement azidomethylene application a la synthese de phenols instables Tetrahedron. ,vol. 44, pp. 6055- 6064 ,(1988) , 10.1016/S0040-4020(01)89794-5
Mirkó Palla, Wenjing Guo, Shundi Shi, Zengmin Li, Jian Wu, Steffen Jockusch, Cheng Guo, James J. Russo, Nicholas J. Turro, Jingyue Ju, DNA sequencing by synthesis using 3′-O-azidomethyl nucleotide reversible terminators and surface-enhanced Raman spectroscopic detection RSC Advances. ,vol. 4, pp. 49342- 49346 ,(2014) , 10.1039/C4RA08398A
Thomas Hagerott, Edmund Golaski, Jerzy Olejnik, Steven Gordon, Methods And Devices For Sequencing Nucleic Acids In Smaller Batches ,(2010)
Petr Klán, Tomas Solomek, Christian G Bochet, Aurélien Blanc, Richard Givens, Marina Rubina, Vladimir Popik, Alexey Kostikov, Jakob Wirz, Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy Chemical Reviews. ,vol. 113, pp. 119- 191 ,(2013) , 10.1021/CR300177K