Prodrugs comprising a pyroglutamate linker
作者： Nicola Bisek , Harald Rau , Samuel Weisbrod
DOI:
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摘要: The present invention relates to novel prodrugs of primary or secondary amine-comprising biologically active moieties and pharmaceutically acceptable salts thereof, prodrug reagents, pharmaceutical compositions comprising said the use prodrugs.
lens.org 参考文章(4)
Ulrich Hersel, Dirk Vetter, Protein carrier-linked prodrugs ,(2012)
Alex S Goldstein, John K Amory, Stephanie M Martin, Chris Vernon, Alvin Matsumoto, Paul Yager, Testosterone delivery using glutamide-based complex high axial ratio microstructures. Bioorganic & Medicinal Chemistry. ,vol. 9, pp. 2819- 2825 ,(2001) , 10.1016/S0968-0896(01)00149-3
Yuzuru Eto, Reiko Yasuda, Prophylactic or therapeutic agent for diabetes or obesity ,(2011)
Alexander V. Kelin, Muthiah Manoharan, Muthusamy Jayaraman, Pachamuthu Kandasamy, Jayaprakash K. Nair, Shigeo Matsuda, Kallanthottathil G. Rajeev, Oligonucleotide-ligand conjugates and process for their preparation ,(2014)