Effect of cooling rate and gelatin concentration on the microstructural and mechanical properties of ice template gelatin scaffolds

作者: Neda Arabi , Ali Zamanian

DOI: 10.1002/BAB.1120

关键词:

摘要: In the current study, a controlled unidirectional freeze casting method was employed to fabricate highly porous gelatin scaffolds. Different concentrations of 1, 3, and 5 wt% were dissolved in distilled water, constant value glutaraldehyde cross-linking agent (0.5 wt%) added solution. Then, solutions casted at different cooling rates 6°C/Min dried. Finally, pore morphology, mechanical properties, water adsorption characteristics scaffolds assessed. Results showed that increase concentration caused shapes change from oblate polygon almost round but rate had no obvious effect on morphology. Compressive strength improved as function 20 1,150 kPa. The decreased with augmentation range 2,000%-500%. Therefore, this study suggests use controllable can tailor could be novel approach avoid toxic dose like glutaraldehyde.

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