Method of immobilizing nucleic acid on a solid surface for use in nucleic acid hybridization assays

作者: Rhonda Lang , Leopoldo G. Mendoza , Chander Bahl

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摘要: Methods of immobilizing nucleic acid on a solid surface for us in hybridization assays is disclosed. The methods the invention comprise reacting modified strand comprising variable portion and an anchor wherein comprises nucleotide sequence having selected base at least one with primary amine function or equivalent free aldehyde group presence reducing agent to form complexes groups surface.

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