作者: Lieke Uijterschout , Marianne Nuijsink , Daniëlle Hendriks , Rimke Vos , Frank Brus
DOI: 10.1002/PPUL.22857
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摘要: In adult CF patients iron deficiency (ID) is common and primarily functional due to chronic inflammation. No recent data are available on the cause of ID anemia (IDA) in children with CF. Over last decades onset inflammation pulmonary disease delayed by improved nutritional status. We questioned whether occurs same extent among as patients. therefore conducted a study investigate status determine IDA associated dietary intake, lung severity Pseudomonas aeruginosa (PA) infection. Clinical charts 53 aged 0-16 were reviewed. Follow-up varied from 1 14 years 343 annual observations total. Thirty-two (60.4%) deficient at least year was present 84 (24.5%). 2011 9 (17.0%). Ten (18.9%) anemic 13 328 (4.0%). 6 (11.3%). Ferritin (Fer) positively age. Higher Fer values found older represent an increased state inflammation, rather than status, might increase relative contribution ID. This shows that relatively healthy, well-nourished The mechanism currently unknown. A prospective using both soluble transferrin receptor indicators for will provide more insight incidence causes