Risk of Psychiatric Disorders in Multiple Sclerosis: A Nationwide Cohort Study in an Asian Population.

作者: Wu-Chien Chien , Yu-Chen Kao , Nian-Sheng Tzeng , Hsin-An Chang , Fang-Jung Wan

DOI: 10.2147/NDT.S268360

关键词:

摘要: Background Multiple sclerosis (MS) is a demyelinating disease that can damage neurons in the brain and spinal cord associated with several psychiatric disorders. However, few studies have evaluated risk of disorders patients MS by using nationwide database. This study investigated association between Methods Using data from Taiwan National Health Insurance Research Database 2000 to 2015, we identified 1066 MS. After adjustment for confounding factors, Fine Gray's competing model was used compare during 15 years follow-up. Results Of MS, 531 (4622.86 per 105 person years) developed disorders; contrast, 891 3198 controls (2485.31 revealed an adjusted hazard ratio (HR) 5.044 (95% confidence interval = 4.448-5.870, p Conclusion Patients were determined higher developing wide range

参考文章(88)
Christian Confavreux, Alastair Compston, The natural history of multiple sclerosis McAlpine's Multiple Sclerosis. ,vol. 56, pp. 183- 272 ,(2006) , 10.1016/B978-0-443-07271-0.50006-9
Hsiang-Yu Yu, Chien Chen, Din-E Shan, Chih-Lun Yuan, Ching-Piao Tsai, Yuh-Cherng Guo, Multiple sclerosis in Taiwan. Journal of The Chinese Medical Association. ,vol. 67, pp. 500- 505 ,(2004)
J.-H. Kang, Y.-H. Chen, H.-C. Lin, Comorbidities amongst patients with multiple sclerosis: a population-based controlled study. European Journal of Neurology. ,vol. 17, pp. 1215- 1219 ,(2010) , 10.1111/J.1468-1331.2010.02971.X
Wei-Sheng Chung, Cheng-Li Lin, Tzung-Chang Tsai, Wu-Huei Hsu, Chia-Hung Kao, Multiple sclerosis increases the risk of venous thromboembolism: a nationwide cohort analysis. European Journal of Clinical Investigation. ,vol. 45, pp. 1228- 1233 ,(2015) , 10.1111/ECI.12502
Lazaros Belbasis, Vanesa Bellou, Evangelos Evangelou, John P A Ioannidis, Ioanna Tzoulaki, Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses. Lancet Neurology. ,vol. 14, pp. 263- 273 ,(2015) , 10.1016/S1474-4422(14)70267-4
B. Wood, I. van der Mei, A.-L. Ponsonby, F. Pittas, S. Quinn, T. Dwyer, R. Lucas, B. Taylor, Prevalence and concurrence of anxiety, depression and fatigue over time in multiple sclerosis Multiple Sclerosis Journal. ,vol. 19, pp. 217- 224 ,(2013) , 10.1177/1352458512450351
L.-M. Sun, C.-L. Lin, C.-J. Chung, J.-A. Liang, F.-C. Sung, C.-H. Kao, Increased breast cancer risk for patients with multiple sclerosis: a nationwide population‐based cohort study European Journal of Neurology. ,vol. 21, pp. 238- 244 ,(2014) , 10.1111/ENE.12267
Chi-Shin Wu, Mei-Shu Lai, Susan Shur-Fen Gau, Sheng-Chang Wang, Hui-Ju Tsai, Concordance between Patient Self-Reports and Claims Data on Clinical Diagnoses, Medication Use, and Health System Utilization in Taiwan PLoS ONE. ,vol. 9, pp. e112257- ,(2014) , 10.1371/JOURNAL.PONE.0112257
Willie Sai Ho Chan, Taiwan’s healthcare report 2010 The Epma Journal. ,vol. 1, pp. 563- 585 ,(2010) , 10.1007/S13167-010-0056-8
Jiunn-Horng Kang, Herng-Ching Lin, Increased Risk of Multiple Sclerosis after Traumatic Brain Injury: A Nationwide Population-Based Study Journal of Neurotrauma. ,vol. 29, pp. 90- 95 ,(2012) , 10.1089/NEU.2011.1936