Hepatic resection of noncolorectal nonneuroendocrine metastases

作者: Alan W. Hemming , Tim D. Sielaff , Steven Gallinger , Mark S. Cattral , Bryce R. Taylor

DOI: 10.1002/LT.500060114

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摘要: Abstract Because hepatic resection is generally a safe procedure,the indications for of noncolorectal nonneuroendocrine (NCNNE) metastases have broadened. The prognostic features NCNNE treated surgically were reviewed to define better the value resection. A retrospective review patients undergoing liver between 1978 and 1998 was undertaken. Thirty-seven identified. Mean age 56 years, with median follow-up 22 months. Primary tumor sites grouped into gastrointestinal (GI) adenocarcinoma (small bowel, n = 4; pancreas, 2; esophagus, 1) other (renal cell, 7; sarcoma, melanoma, 5; adrenal, 3; unknown adenocarcinoma, thyroid, testicular, 1; ovarian, breast, 1). All underwent surgery cure. Metastases synchronous in 14 patients. There no surgical mortality. Overall 5-year survival rate 45%. Five-year rates non-GI-origin (60% v 0%; P .01). Long-term seen only metastases. extent resection, presence metastases, or disease-free interval from time original disease presentation not predictive outcome. We conclude that can undergo an expectation prolonged survival. However, GI primary tumors than colorectum are unlikely show extended

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