Insulin receptors facilitate insulin transport into the central nervous system
作者： Gail D. Baura , David M. Foster , Michael W. Schwartz
DOI: 10.1109/IEMBS.1992.5761454
关键词:
摘要: Insulin is hypothesized to be a negative feedback signal which reflects body adiposity the brain for weight regulation. By showing that uptake of plasma insulin into cerebrospinal fluid saturable, we provide evidence circulating enters central nervous system via endothelial blood-brain barrier receptor. This transport may play an important role in
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