Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes.

作者: M. H. Hesse , L. M. , He , P. , Krishnaswamy

DOI: 10.1097/00008571-200404000-00002

关键词:

摘要: Bupropion is primarily metabolized in human liver by cytochrome P450 (CYP) 2B6, an isoform that shows high interindividual variability in expression and catalysis. The aim of this study …

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